Lesão renal aguda e COVID-19 em adultos jovens na terapia intensiva / Lesión renal aguda y COVID-19 en adultos jóvenes en cuidados intensivos / Acute kidney injury and COVID-19 in young adults in intensive care

Resumo Objetivo Descrever a prevalência de lesão renal aguda em adultos jovens com diagnóstico da COVID-19 admitidos em unidade terapia intensiva. Métodos Estudo retrospectivo, quantitativo e analítico. A amostra foi de adultos jovens (20 a 40 anos) admitidos em unidades de terapia intensiva, com diagnóstico de infecção por SARS-CoV-2 entre março e dezembro de 2020. Os dados foram obtidos por meio do prontuário eletrônico, e a lesão renal aguda foi definida pelo valor da creatinina, segundo critérios das diretrizes da Kidney Disease Improving Global Outcomes. A significância estatística foi de p≤0,05. Resultados Foram internados 58 adultos jovens, sendo 63,8% do sexo masculino. A hipertensão arterial sistêmica esteve presente em 39,6%, a obesidade em 18,9% e o diabetes mellitus em 8,6%. A lesão renal aguda foi identificada em 55,1%, sendo o estágio 3 predominante em 43,1% deles. Nesses pacientes, o uso de ventilação mecânica e de drogas vasoativas foi significativo em 92%, assim como a disfunção orgânica respiratória (80%), seguida da renal (76%). Fatores de risco, como transplante renal ou doença renal crônica e obesidade, aumentaram em 12,3 e 9,0 vezes, respectivamente, a chance de desenvolver lesão renal aguda. Conclusão Este estudo demonstrou alta prevalência de lesão renal em adultos jovens e sua associação com comorbidades prévias. Obesidade, transplante renal e doença renal crônica elevaram a chance de o adulto jovem desenvolver lesão renal aguda, resultando em desfechos a favor da morbimortalidade.

Resumen Objetivo Describir la prevalencia de lesión renal aguda en adultos jóvenes con diagnóstico de COVID-19 admitidos en unidad de cuidados intensivos. Métodos Estudio retrospectivo, cuantitativo y analítico. La muestra fue de adultos jóvenes (20 a 40 años) admitidos en unidades de cuidados intensivos, con diagnóstico de infección por SARS-CoV-2 entre marzo y diciembre de 2020. Los datos se obtuvieron por medio de historias clínicas electrónicas, y la lesión renal aguda fue definida por el valor de la creatinina, de acuerdo con criterios de las directrices de la Kidney Disease Improving Global Outcomes. La significación estadística fue de p≤0,05. Resultados Hubo 58 adultos jóvenes internados, el 63,8 % de sexo masculino. La hipertensión arterial sistémica estuvo presente en el 39,6 %, la obesidad en el 18,9 % y la diabetes mellitus en el 8,6 %. Se identificó lesión renal aguda en el 55,1 %, de nivel 3 como predominante en el 43,1 % de los casos. En esos pacientes, el uso de ventilación mecánica y de drogas vasoactivas fue significativo en el 92 %, así como también la disfunción orgánica respiratoria (80 %), seguida de la renal (76 %). Los factores de riesgo, como trasplante renal o enfermedad renal crónica y obesidad, aumentaron 12,3 y 9,0 veces respectivamente la probabilidad de presentar lesión renal aguda. Conclusión Este estudio demostró alta prevalencia de lesión renal en adultos jóvenes y su asociación con comorbilidades previas. La obesidad, el trasplante renal y la enfermedad renal crónica aumentaron la probabilidad de que los adultos jóvenes presenten lesión renal aguda, lo que da como resultado desenlaces a favor de la morbimortalidad.

Abstract Objective To describe acute kidney injury prevalence in young adults diagnosed with COVID-19 admitted to the Intensive Care Unit. Methods This is a retrospective, quantitative and analytical study. The sample consisted of young adults (20 to 40 years old) admitted to Intensive Care Units, diagnosed with SARS-CoV-2 infection between March and December 2020. Data were obtained through electronic medical records, and kidney injury acute was defined by the creatinine value, according to the Kidney Disease Improving Global Outcomes guidelines criteria. Statistical significance was p≤0.05. Results A total of 58 young adults were hospitalized, 63.8% of whom were male. Hypertension was present in 39.6%, obesity in 18.9%, and diabetes mellitus in 8.6%. Acute kidney injury was identified in 55.1%, with stage 3 predominating in 43.1% of them. In these patients, the use of mechanical ventilation and vasoactive drugs was significant in 92% as well as respiratory organ dysfunction (80%), followed by renal organ dysfunction (76%). Risk factors such as kidney transplantation or chronic kidney disease and obesity increased by 12.3 and 9.0 times, respectively, the chances of developing acute kidney injury. Conclusion This study demonstrated a high kidney injury prevalence in young adults and its association with previous comorbidities. Obesity, kidney transplantation and chronic kidney disease increased the chance of young adults to develop acute kidney injury, resulting in outcomes in favor of morbidity and mortality.

Sociodemographic factors associated with suicidal behavior at a federal public university in the Western Brazilian Amazon.

OBJECTIVE: to determine risk factors for suicidal behavior among students and employees of a federal public university in the Brazilian Western Amazon. METHODS: an analytical cross-sectional study of survey and association between variables with a sample of 475 participants. Statistical analyzes were performed using the Mann-Whitney test, Pearson's chi-square test, likelihood ratio test or Fisher's exact test and a logistic regression model. A significance level of 5% was used (p-value< 0.05). RESULTS: a higher proportion of suicidal behavior was found in younger participants, females, who had no religion or had one, but were non-practicing, who did not have children and/or had a monthly family income of less than two minimum wages. Lower proportions of suicidal behavior were identified in heterosexuals and/or married or in a stable relationship. CONCLUSION: the study suggests a relationship between sociodemographic factors and suicidal behavior in the studied academic community.

Alterações bioquímicas de pacientes com COVID-19 / Alteraciones bioquímicas de pacientes con COVID-19 / Biochemical changes in patients with COVID-19

Resumo Objetivo identificar as alterações bioquímicas dos pacientes com apresentação moderada e grave da doença Covid-19 e as preditivas de gravidade nos que evoluíram do estagio moderado para o grave. Métodos Estudo de coorte prospectivo com 709 pacientes internados com diagnóstico confirmado de COVID-19 e apresentação moderada e grave da doença. Foi realizado em um hospital universitário de média e alta complexidade do estado de São Paulo, no período de abril de 2020 a dezembro de 2021. Os dados coletados dos prontuários foram exames laboratoriais e evolução clínica dos pacientes. Na análise descritiva, foi utilizado frequência absoluta, percentual, média e desvio padrão. Os Testes do Qui-Quadrado de Pearson, Exato de Fisher, Mann-Whitney ou t de Student foram utilizados para comparar as diferenças entre os grupos dos moderados e graves. O nível de significância adotado foi de 0,05. Resultados A média de idade foi significantemente maior nos pacientes graves em relação aos moderados (p<0,001). Os valores da hemoglobina e plaquetas foram estatisticamente menores na internação no grupo dos pacientes graves, proteína C-reativa e D-Dímero, maiores (p<0,001). O número de óbitos foi significantemente maior nos pacientes que foram internados em estado grave (p<0,001) e verificamos também que a hemoglobina e plaquetas estavam abaixo dos valores de referência na internação deste grupo. Dos 533 pacientes que internaram em estado moderado, 38 evoluiram para quadro grave. Conclusão Os resultados mostram a importância da avaliação clínica das variáveis bioquímicas no momento da internação como preditivas de gravidade. Os achados reportados nesta investigação corroboram com dados da literatura e podem elucidar intervenções precoces para melhor manejo dos pacientes desde o momento da internação.

Resumen Objetivo Identificar las alteraciones bioquímicas de los pacientes con cuadro moderado y grave de la enfermedad de COVID-19 y las predictivas de gravedad en los que evolucionaron de nivel moderado a grave. Métodos Estudio de cohorte prospectivo con 709 pacientes internados con diagnóstico confirmado de COVID-19 y cuadro moderado y grave de la enfermedad. Fue realizado en un hospital universitario de complejidad mediana y alta en el estado de São Paulo, durante el período de abril de 2020 a diciembre de 2021. Los datos obtenidos a partir de las historias clínicas fueron pruebas de laboratorio y evolución clínica de los pacientes. En el análisis descriptivo se utilizó frecuencia absoluta, porcentaje, promedio y desviación típica. Para comparar las diferencias entre los grupos de los moderados y graves se utilizaron las pruebas χ2 de Pearson, exacta de Fisher, Mann-Whitney o t de Student. El nivel de significación adoptado fue de 0,05. Resultados El promedio de edad fue considerablemente más alto en los pacientes graves en relación con los moderados (p<0,001). Los valores de la hemoglobina y de las plaquetas fueron estadísticamente inferiores en la internación en el grupo de los pacientes graves, proteína C reactiva y dímero D, superiores (p<0,001). El número de defunciones fue considerablemente más alto en los pacientes que ingresaron en estado grave (p<0,001) y verificamos también que la hemoglobina y las plaquetas estaban por debajo de los valores de referencia en la internación de este grupo. De los 533 pacientes que ingresaron en estado moderado, 38 evolucionaron hacia cuadros graves. Conclusión Los resultados muestran la importancia de la evaluación clínica de las variables bioquímicas en el momento de la internación como predictivas de gravedad. Los resultados informados en esta investigación confirman los datos de la literatura y pueden esclarecer intervenciones tempranas para un mejor manejo de los pacientes desde el momento de la internación.

Abstract Objective To identify the biochemical alterations of patients with moderate and severe COVID-19 and the predictors of severity in those who progressed from the moderate to the severe stage. Methods This is a prospective cohort study with 709 patients hospitalized with a confirmed diagnosis of COVID-19 and moderate and severe illness. It was carried out in a university hospital of medium and high complexity, in the state of São Paulo, from April 2020 to December 2021. Data collected from medical records were laboratory tests and clinical progression of patients. In the descriptive analysis, absolute frequency, percentage, mean and standard deviation were used. Pearson's chi-square, Fisher's exact, Mann-Whitney or Student's t tests were used to compare the differences between the moderate and severe groups. The significance level adopted was 0.05. Results The mean age was significantly higher in severe patients than in moderate ones (p<0.001). Hemoglobin and platelet values were statistically lower upon admission in the group of critically ill patients, C-reactive protein and D-dimer higher (p<0.001). The number of deaths was significantly higher in patients who were hospitalized in a serious condition (p<0.001) and we also found that hemoglobin and platelets were below the reference values at hospitalization in this group. Of the 533 patients who were hospitalized in a moderate condition, 38 progressed to a severe condition. Conclusion The results show the importance of clinical assessment of biochemical variables at the time of admission as predictors of severity. The findings reported in this investigation corroborate data from the literature and can elucidate early interventions for better management of patients from the moment of hospitalization.

Qualidade do sono e burnout em docentes do ensino superior / Sleep quality and burnout in higher education teachers

RESUMO Objetivo avaliar a associação da qualidade do sono e presença da síndrome de burnout com o perfil epidemiológico de docentes do ensino superior. Métodos estudo observacional, analítico, do tipo transversal, realizado com 140 docentes, por meio do Índice de Qualidade do Sono de Pittsburgh e Maslach Burnout Inventory. Resultados na amostra, a maioria era do sexo feminino (54,3%), com idades entre 26 e 40 anos (58,6%). Houve predomínio de docentes com título de especialista (48,6%), com faixa salarial de até R$ 5.000,00 (85,7%), com dois ou mais vínculos empregatícios (52,1%). Constatou-se que docentes que recebiam mais de R$ 5.000,00 (p=0,003), com dois ou mais empregos, classificaram a eficiência habitual do sono como ruim/muito ruim (p=0,027). Todavia, aqueles com qualidade subjetiva do sono boa apresentaram menores escores nos domínios Exaustão emocional (p=0,005) e Despersonalização em relação à referida síndrome (p=0,023). Conclusão diversos fatores colaboram para o desenvolvimento de distúrbios relacionados ao sono na classe docente, tornando-a mais suscetível à manifestação do burnout. Contribuições para a prática os resultados podem subsidiar medidas preventivas para a saúde dos docentes e manutenção da qualidade de suas atividades laborais, visando diminuir o efeito-mediação das variáveis que favorecem o esgotamento psicológico.

ABSTRACT Objective to evaluate the association of sleep quality and the presence of burnout syndrome with the epidemiological profile of higher education teachers. Methods an observational, analytical, cross-sectional study of 140 teachers, using the Pittsburgh Sleep Quality Index and the Maslach Burnout Inventory. Results in the sample, the majority was female (54.3%), aged between 26 and 40 years (58.6%). There was a predominance of teachers with a specialist title (48.6%), with a salary range of up to R$ 5,000.00 (85.7%), with two or more employment relationships (52.1%). It was found that teachers who received more than R$ 5,000.00 (p=0.003), with two or more jobs, classified the usual sleep efficiency as poor/feeble (p=0.027). However, those with good subjective sleep quality had lower scores in the Emotional exhaustion (p=0.005) and Depersonalization domains in relation to the syndrome (p=0.023). Conclusion several factors contribute to the development of sleep-related disorders in teachers, making them more susceptible to the manifestation of burnout. Contributions to practice the results can support preventive measures for the health of teachers and maintain the quality of their work activities, aiming to reduce the mediation effect of the variables that favor psychological exhaustion.

Atividades de vida diária, sintomas depressivos e qualidade de vida de idosos / Actividades de la vida diaria, síntomas depresivos y calidad de vida de los adultos mayores / Elderly's activities of daily living, depressive symptoms and quality of life

Resumo Objetivo Correlacionar os sintomas depressivos com a capacidade de realização das atividades básicas de vida diária e a qualidade de vida em idosos residentes em instituições de longa permanência. Métodos Estudo transversal, com amostra constituída por 99 idosos, residentes nas dez instituições de longa permanência para idosos públicas da cidade de São Paulo. Na coleta de dados utilizou-se os instrumentos Whoquol Bref e Old, Inventário de Depressão de Beck e Índice de Katz. Os dados foram coletados no período de julho de 2016 a fevereiro de 2019 e o tratamento estatístico foi realizado utilizando o software Statistical Package for the Social Sciences® (SPSS - versão 24.0). Resultado Os idosos têm uma perceção positiva da sua qualidade de vida correlacionada com a independência para as atividades básicas de vida diária, com significância estatística para os domínios funcionamento sensorial (r = ,263), físico (r = ,200) e psicológico (r = ,214). E uma avaliação negativa em relação a sintomas depressivos nos domínios funcionamento sensorial (r = -,438), autonomia (r = -,310), atividade passada, presente e futura (r = -,384), participação social (r = -,368), morte e morrer (r = -,913), intimidade (r = -,351), físico (r = -,590), psicológico (r = -,539), relações sociais (r = -,382) e meio ambiente (r = -,533). Conclusão Os idosos independentes apresentaram melhores escores nos domínios funcionamento sensorial, físico e psicológico; já os com sintomas depressivos demostraram piores escores em todos os domínios da qualidade de vida.

Resumen Objetivo Correlacionar los síntomas depresivos con la capacidad de realización de las actividades básicas de la vida diaria y la calidad de vida en adultos mayores residentes en instituciones de larga permanencia. Métodos Estudio transversal, con una muestra formada por 99 adultos mayores, residentes en las diez instituciones públicas de larga permanencia para adultos mayores en la ciudad de São Paulo. Para la recopilación de datos se utilizaron los instrumentos Whoquol Bref y Old, Inventario de Depresión de Beck e Índice de Katz. El período de recopilación de datos ocurrió de julio de 2016 a febrero de 2019 y el tratamiento estadístico se realizó utilizando el software Statistical Package for the Social Sciences® (SPSS - versión 24.0). Resultados Los adultos mayores tienen una percepción positiva de su calidad de vida que se correlaciona con la independencia para las actividades básicas de vida diaria, con significación estadística para los dominios funcionamiento sensorial (r = ,263), físico (r = ,200) y psicológico (r = ,214). Es una evaluación negativa con relación a síntomas depresivos en los dominios funcionamiento sensorial (r = -,438), autonomía (r = -,310), actividad pasada, presente y futura (r = -,384), participación social (r = -,368), muerte y morir (r = -,913), intimidad (r = -,351), físico (r = -,590), psicológico (r = -,539), relaciones sociales (r = -,382) y medioambiente (r = -,533). Conclusión Los adultos mayores independientes presentaron mejor puntuación en los dominios funcionamiento sensorial, físico y psicológico; con los síntomas depresivos demostraron peor puntuación en todos los dominios de la calidad de vida.

Abstract Objective To correlate depressive symptoms with the ability to perform activities of daily living and the quality of life of elderly people living in Nursing Homes. Methods This is a cross-sectional study, with a sample consisting of 99 elderly people, living in ten public Nursing Homes in the city of São Paulo. Data collection used the instruments WHOQOL Bref and Old, Beck Depression Inventory and Katz Index. Data were collected from July 2016 to February 2019 and statistical treatment was performed using the Statistical Package for Social Sciences® (SPSS - version 24.0). Results The elderly have a positive perception of their quality of life correlated with independence for activities of daily living, with statistical significance for sensory functioning (r = .263), physical (r = .200) and psychological (r = .214) domains; and a negative assessment in relation to depressive symptoms in sensory functioning (r = -.438), autonomy (r = -.310), past, present, and future activities (r = -.384), social participation (r = - .368), death and dying (r = -.913), intimacy (r = -.351), physical (r = -.590), psychological (r = -.539), social relationships (r = -.382), and environment (r = -.533) domains. Conclusion Independent elderly had better scores in sensory functioning, physical and psychological domains. Those with depressive symptoms had worse scores in all quality of life domains.

Urinary tract infection in patients with chronic kidney disease under conservative treatment / Infección del tracto urinario en pacientes con enfermedad renal crónica en tratamiento conservador / Infecção do trato urinário em pacientes com doença renal crônica em tratamento conservador

ABSTRACT Objectives: to assess the prevalence and associated risk factors for urinary tract infection in patients with chronic kidney disease under conservative treatment and identify the microorganisms isolated in the urine of these patients and the staging of chronic kidney disease. Methods: a cross-sectional, analytical study carried out at the Conservative Treatment Outpatient Clinic of a university hospital in the city of São Paulo. Results: the prevalence of urinary tract infection is 22%. The risk factors Diabetes Mellitus, hypertension, heart disease, neoplasms and thyroid and autoimmune diseases stand out in the infected group (p < 0.001). Most of the microorganisms found in urine cultures (87.9%) were Gram-negative, being Escherichia coli (50.70%), followed by Klebsiella pneumoniae (23.1%) and Enterococcus spp. (9.7%). Conclusions: the findings of this investigation reveal the intrinsic association between risk factors and microorganisms for the development of urinary tract infection.

RESUMEN Objetivos: evaluar la prevalencia y los factores de riesgo asociados de infección del tracto urinario en pacientes con enfermedad renal crónica en tratamiento conservador e identificar los microorganismos aislados en la orina de estos pacientes y la estadificación de la enfermedad renal crónica. Métodos: estudio transversal, analítico, realizado en el Ambulatorio de Tratamiento Conservador de un hospital universitario de la ciudad de São Paulo. Resultados: la prevalencia de infección del tracto urinario es del 22%. Los factores de riesgo de diabetes mellitus, hipertensión arterial sistémica, cardiopatías, neoplasias y enfermedades tiroideas y autoinmunes destacan en el grupo con infección (p <0,001). La mayoría de los microorganismos encontrados en los urocultivos (87,9%) fueron Gram negativos, siendo Escherichia coli (50,70%), seguida de Klebsiella pneumoniae (23,1%) y Enterococcus spp. (9,7%). Conclusiones: los hallazgos de esta investigación revelan la asociación intrínseca entre factores de riesgo y microorganismos para el desarrollo de infección del tracto urinario.

RESUMO Objetivos: avaliar a prevalência e os fatores de risco associados para infecção do trato urinário em pacientes com doença renal crônica em tratamento conservador e identificar os microrganismos isolados na urina desses pacientes e o estadiamento da doença renal crônica . Métodos: estudo transversal, analítico, realizado no Ambulatório de Tratamento Conservador de um hospital universitário da cidade de São Paulo. Resultados: a prevalência de infecção do trato urinário é de 22%. Destacam-se no grupo com infecção os fatores de risco Diabetes Mellitus, hipertensão arterial sistêmica, doença cardíaca, neoplasias e doenças da tireoide e autoimunes (p<0,001). Em sua maioria (87,9%), os microrganismos encontrados nas uroculturas foram Gram-negativos, sendo Escherichia coli (50,70%), seguida de Klebsiella pneumoniae (23,1%) e Enterococcus spp. (9,7%). Conclusões: os achados desta investigação revelam a intrínseca associação entre os fatores de risco e os microrganismos para o desenvolvimento da infecção do trato urinário.

Fatores associados à qualidade de vida da pessoa idosa em instituições de longa permanência públicas / Factores relacionados con la calidad de vida de las personas mayores en instituciones públicas de larga estancia / Factors associated with the quality of life of the elderly in public long-stay institutions

Objetivo: avaliar a qualidade de vida de idosos institucionalizados e sua associação a variáveis sociodemográficas, sintomas de depressão e capacidade de autocuidado. Método: estudo transversal, entre 2017 e 2019, com amostra de 99 idosos. A coleta foi realizada por meio de entrevista dirigida em sala privativa. Associações foram testadas por regressão linear multivariada, adotando p<0,05. Resultados: sintoma depressivo piora a qualidade de vida; maior tempo de moradia e liberdade para sair da instituição melhoram a percepção de atividades passadas, presentes e futuras, participação social e ser analfabeto em ambos; os dependentes estão satisfeitos com o ambiente e participação social; receber visita melhora o psicológico e relações sociais; limitação de movimentos prejudica o físico; e idade superior a 70 anos prejudica as relações sociais. Conclusão: ambiente que estimule a saúde mental e física e as relações e participações sociais são fatores que melhoram a qualidade de vida dos idosos.

Objective: to evaluate the quality of life of the institutionalized elderly and its association with sociodemographic variables, symptoms of depression and self-care capacity. Method: cross-sectional study, between 2017 and 2019, with a sample of 99 elderly people. The collection was performed through an interview conducted in a private room. Associations were tested by multivariate linear regression, adopting p<0.05. Results: depressive symptom worsens quality of life; longer time living and freedom to leave the institution improve the perception of past, present and future activities, social participation and being illiterate in both; Dependents are satisfied with the environment and social participation; receiving visit improves the psychological and social relations; limitation of movements harms the physical; and age over 70 harms social relations. Conclusion: environment that stimulates mental and physical health and relationships and social participation are factors that improve the quality of life of the elderly.

Objetivo: evaluar la calidad de vida de ancianos institucionalizados y su asociación a variables sociodemográficas, síntomas de depresión y capacidad de autocuidado. Método: estudio transversal, entre 2017 y 2019, con muestra de 99 ancianos. La colecta fue realizada por medio de entrevista dirigida en sala privada. Las asociaciones fueron probadas por regresión lineal multivariada, adoptando p<0,05. Resultados: síntoma depresivo empeora la calidad de vida; mayor tiempo de vivienda y libertad para salir de la institución mejoran la percepción de actividades pasadas, presentes y futuras, participación social y ser analfabeto en ambos; los dependientes están satisfechos con el ambiente y participación social; recibir visita mejora lo psicológico y relaciones sociales; limitación de movimientos perjudica lo físico; y edad superior a 70 años perjudica las relaciones sociales. Conclusión: ambiente que estimule la salud mental y física y las relaciones y participaciones sociales son factores que mejoran la calidad de vida de los ancianos.

Religious/spiritual experiences, quality of life and satisfaction with life of hospitalized octogenarians / Experiencias religiosas/espirituales, calidad de vida y satisfacción con la vida de octogenarios hospitalizados / Experiências religiosas/espirituais, qualidade de vida e satisfação com a vida de octogenários hospitalizados

ABSTRACT Objectives: to assess quality of life (QoL) and satisfaction with life (SWL) indices and verify whether the frequency of religious and spiritual experiences is associated with QoL and SWL in hospitalized octogenarians. Method: this is a cross-sectional study, with 128 octogenarians. World Health Organization QoL instruments and Scales applied: Daily Spiritual Experience (DSES) and Satisfaction With Life (SWLS). Results: more committed domains related to QoL and SWL: autonomy and physical capacity. The higher the score in DSES, the higher the scores in the psychological domains and past, present, and future QoL activities. The higher the score in DSES, the higher the score in the social involvement aspect. Conclusion: the results of this study showed that the higher frequency of religious and spiritual experiences of hospitalized elderly people was associated with better QoL and SWL. It is emphasized that religious and spiritual experiences should be explored in the hospital therapeutic context.

RESUMEN Objetivos: evaluar índices de calidad de vida (CV) y satisfacción con la vida (SV) y verificar si la frecuencia de experiencias religiosas y espirituales está asociada a CV y ​​SV en octogenarios hospitalizados. Método: transversal, 128 octogenarios. Instrumentos y escalas de calidad de vida de la Organización Mundial de la Salud aplicados: Experiencia Espiritual Diaria (EDEE) y Satisfacción con la Vida (ESV). Resultados: dominios más comprometidos relacionados con CV y ​​VS: autonomía y capacidad física. Cuanto mayor sea la puntuación EDEE, mayores serán las puntuaciones en los dominios psicológico y pasado, presente y futuro de calidad de vida. Cuanto mayor sea la puntuación en la EDEE, mayor será la puntuación en el aspecto de implicación social de la ESV. Conclusión: los resultados de este estudio mostraron que la mayor frecuencia de experiencias religiosas y espirituales de los ancianos hospitalizados se asoció con una mejor CV y SS. Se enfatiza que las experiencias religiosas y espirituales deben ser exploradas en el contexto terapéutico hospitalario.

RESUMO Objetivos: avaliar índices de qualidade de vida (QV) e de satisfação com a vida (SV) e verificar se a frequência de experiências religiosas e espirituais se associa à QV e à SV em octogenários hospitalizados. Método: transversal, 128 octogenários. Aplicados instrumentos de QV da Organização Mundial da Saúde e Escalas: Diária de Experiência Espiritual (EDEE) e de Satisfação com a Vida (ESV). Resultados: domínios mais comprometidos relacionados à QV e à SV: autonomia e capacidade física. Quanto maior a pontuação na EDEE, maiores os escores nos domínios psicológico e atividades passadas, presentes e futuras de QV. Quanto maior a pontuação na EDEE, maior o escore no aspecto envolvimento social da ESV. Conclusão: os resultados deste estudo mostraram que a maior frequência de experiências religiosas e espirituais dos idosos hospitalizados associou-se com a melhor QV e SV. Ressalta-se que as experiências religiosas e espirituais devem ser exploradas no contexto terapêutico hospitalar.

Urinary tract infection in patients with chronic kidney disease under conservative treatment.

OBJECTIVES: to assess the prevalence and associated risk factors for urinary tract infection in patients with chronic kidney disease under conservative treatment and identify the microorganisms isolated in the urine of these patients and the staging of chronic kidney disease. METHODS: a cross-sectional, analytical study carried out at the Conservative Treatment Outpatient Clinic of a university hospital in the city of São Paulo. RESULTS: the prevalence of urinary tract infection is 22%. The risk factors Diabetes Mellitus, hypertension, heart disease, neoplasms and thyroid and autoimmune diseases stand out in the infected group (p < 0.001). Most of the microorganisms found in urine cultures (87.9%) were Gram-negative, being Escherichia coli (50.70%), followed by Klebsiella pneumoniae (23.1%) and Enterococcus spp. (9.7%). CONCLUSIONS: the findings of this investigation reveal the intrinsic association between risk factors and microorganisms for the development of urinary tract infection.

Infectious events in kidney transplant recipients from deceased expanded criteria donors: a prospective cohort.

OBJECTIVE: Analyze risk factors for infection in kidney transplant recipients from deceased expanded criteria donors (DECD) in the first two years of follow-up. METHOD: This is a prospective cohort study with 466 patients from DECD who underwent kidney transplantation in 2015 and 2016 in Brazil. A total of 551 events were recorded. The largest incidence of infectious events occurred in the first month after kidney transplantation. Cytomegalovirus infection was the most common infectious episode. RESULTS: The incidence rate of infections was 57.1%. Among bacterial infections, only 4% were due to multidrug-resistant microorganisms. The death rate was 3.3% (15) patients. The main cause of death was infectious (73.3%). Hospitalization until the first infection (aOR:1.61), Number of infections in 1 year (aOR:40.16), and Cytomegalovirus infection (aOR:13.84) was risk factors for infection by multidrug resistant microorganisms (MDR). CONCLUSION: Infection incidence with MDR bacteria was high among kidney transplant recipients from DECD, and the main cause of death was infection. Survival was high among patients with infection.

Religious/spiritual experiences, quality of life and satisfaction with life of hospitalized octogenarians.

OBJECTIVES: to assess quality of life (QoL) and satisfaction with life (SWL) indices and verify whether the frequency of religious and spiritual experiences is associated with QoL and SWL in hospitalized octogenarians. METHOD: this is a cross-sectional study, with 128 octogenarians. World Health Organization QoL instruments and Scales applied: Daily Spiritual Experience (DSES) and Satisfaction With Life (SWLS). RESULTS: more committed domains related to QoL and SWL: autonomy and physical capacity. The higher the score in DSES, the higher the scores in the psychological domains and past, present, and future QoL activities. The higher the score in DSES, the higher the score in the social involvement aspect. CONCLUSION: the results of this study showed that the higher frequency of religious and spiritual experiences of hospitalized elderly people was associated with better QoL and SWL. It is emphasized that religious and spiritual experiences should be explored in the hospital therapeutic context.

Anxiety level of public university employees with suspected or confirmed COVID-19 infection.

Introduction: Workers on leave awaiting confirmation of coronavirus infection may experience worry and anticipatory stress. Objectives: The objective of this study was to assess the anxiety levels of employees at a public university in the state of São Paulo who were put on leave due to suspected or confirmed SARS-CoV-2 infection and to correlate their anxiety levels with personal and work-related variables. Methods: This cross-sectional study used an online survey to collect data from employees who took a diagnostic test for COVID-19. The participants' anxiety level was measured using Greenberger and Padesky's Anxiety Inventory, while data on personal and work-related variables were collected through a socio-demographic questionnaire. Results: Most of the 153 participants (76.5%) reported anxiety symptoms. COVID-19 infection was confirmed in 51%. The highest prevalence of severe anxiety (27%) was among employees who had indirect contact with COVID-19 patients. Three variables - being a woman, being a regular employee, and previous physical health problems - were responsible for a higher risk of anxiety. Conclusions: This study's findings indicate the need to protect the mental health of the university's employees.

Causas de óbitos em hospital de ensino da Amazônia Ocidental brasileira / Causas de fallecimiento en hospital universitario de la Amazonía Occidental brasileña / Causes of death in a teaching hospital of the Brazilian western Amazon

Resumo Objetivo Identificar o perfil epidemiológico dos pacientes que evoluíram para óbito, caracterizar essas mortes segundo variáveis sociodemográficas e clínicas e analisar a relação entre a causa básica e a causa imediata do óbito em um hospital de ensino. Métodos Estudo quantitativo, transversal retrospectivo, com componentes descritivos, utilizando como principal fonte de dados os atestados de óbitos do Sistema de Informações do Sistema Único de Saúde e das declarações de óbitos ocorridos em 2016 da instituição pesquisada. Resultados Dos 634 óbitos, a maioria dos pacientes era do sexo masculino (56,9%), sendo 70% de afrodescendentes, observou-se que quase metade (48,8%) tinha 65 anos ou mais de idade, acometeu 50,7% dos homens acima dos 66 anos e 53,8% das mulheres com menos de 66 anos. As principais causas imediatas de morte foram associadas às neoplasias (45,4%) e às doenças infecciosas e parasitárias (28,9%). Quanto as declarações de óbitos, existe uma subnotificação nas causas consequenciais 2 e 3, de 12,6% e 49,9%, respectivamente. Conclusão A ocorrência de doenças infecciosas e parasitárias, os sinais/sintomas e exames clínicos/laboratoriais alterados, exerceram impacto importante como causa imediata dos óbitos analisados. Destaca-se que os óbitos por neoplasias se mantiveram constantes em todas as categorias (causa imediata, causa consequencial 2, causa consequência 3, causa básica).

Resumen Objetivo Identificar el perfil epidemiológico de los pacientes que fallecieron, caracterizar esas muertes de acuerdo con variables sociodemográficas y clínicas y analizar la relación entre la causa básica y la causa directa del fallecimiento en un hospital universitario. Métodos Estudio cuantitativo, transversal retrospectivo, con componentes descriptivos, utilizando como principal fuente de datos los certificados de defunción del Sistema de Información del Sistema Único de Salud y las declaraciones de las defunciones ocurridas en 2016 en la institución estudiada. Resultados De los 634 fallecimientos, la mayoría de los pacientes era de sexo masculino (56,9 %), el 70 % era afrodescendiente. Se observó que casi la mitad (48,8 %) tenía 65 años o más, el 50,7 % de los hombres tenía más de 66 años y el 53,8 % de las mujeres, menos de 66 años. Las principales causas directas de muerte se asociaron con neoplasias (45,4 %) y enfermedades infecciosas y parasitarias (28,9 %). Respecto a las declaraciones de defunción, existe una subnotificación en la causa antecedente 2 del 12,6 % y en la 3 del 49,9 %. Conclusión Los casos de enfermedades infecciosas y parasitarias, los signos/síntomas y estudios clínicos/de laboratorio alterados ejercieron un importante impacto como causa directa de los fallecimientos analizados. Se observa que los fallecimientos por neoplasias se mantuvieron constantes en todas las categorías (causa directa, causa antecedente 2, causa antecedente 3, causa básica).

Abstract Objectives To identify the epidemiological profile of patients who died, to characterize these deaths according to sociodemographic and clinical variables and to analyze the relation between the underlying cause and immediate cause of death in a teaching hospital. Methods Quantitative cross-sectional study, with descriptive components, using as the main source of data the death certificates of the Information System of the Brazilian Unified Health System and the death declarations that occurred in 2016 in the institution studied. Results Of the 634 deaths, most of the patients were male (56.9%), being 70% Afro-descendants; it was observed that almost half (48.8%) were 65 years of age or older; it affected 50.7% of men over 66 years and 53.8% of women under 66 years. The main immediate causes of death were associated with neoplasms (45.4%) and infectious and parasitic diseases (28.9%). Regarding death declarations, there is an underreporting in consequential causes 2 and 3, of 12.6% and 49.9%, respectively. Conclusion The occurrence of infectious and parasitic diseases, the signs/symptoms and altered clinical/laboratory tests had an important impact as immediate cause of the analyzed deaths. It is noteworthy that deaths from neoplasms remained constant in all categories (immediate cause, consequential cause 2, consequential cause 3, and underlying cause).

Infectious events in kidney transplant recipients from deceased expanded criteria donors: a prospective cohort / Eventos infecciosos en receptores de trasplante renal de donante fallecido con criterios expandidos: cohorte prospectiva / Eventos infecciosos em receptores de transplante renal de doador falecido com critério expandido: coorte prospectiva

ABSTRACT Objective: Analyze risk factors for infection in kidney transplant recipients from deceased expanded criteria donors (DECD) in the first two years of follow-up. Method: This is a prospective cohort study with 466 patients from DECD who underwent kidney transplantation in 2015 and 2016 in Brazil. A total of 551 events were recorded. The largest incidence of infectious events occurred in the first month after kidney transplantation. Cytomegalovirus infection was the most common infectious episode. Results: The incidence rate of infections was 57.1%. Among bacterial infections, only 4% were due to multidrug-resistant microorganisms. The death rate was 3.3% (15) patients. The main cause of death was infectious (73.3%). Hospitalization until the first infection (aOR:1.61), Number of infections in 1 year (aOR:40.16), and Cytomegalovirus infection (aOR:13.84) was risk factors for infection by multidrug resistant microorganisms (MDR). Conclusion: Infection incidence with MDR bacteria was high among kidney transplant recipients from DECD, and the main cause of death was infection. Survival was high among patients with infection.

RESUMEN Objetivo: Analizar los factores de riesgo de infección en receptores de trasplante renal de donante fallecido con criterios expandidos (DFCE) en los dos primeros años de seguimiento. Método: Estudio prospectivo de cohorte con 466 pacientes con DFCE sometidos a trasplante renal, en 2015 y 2016, en Brasil. Se registraron un total de 551 eventos. La mayor incidencia de eventos infecciosos ocurrió en el primer mes después del trasplante de riñón. La infección por citomegalovirus fue el episodio infeccioso más común. Resultados: La tasa de incidencia de infecciones fue del 57,1%. Entre las infecciones bacterianas, solo el 4% se debió a microorganismos multirresistentes. La tasa de mortalidad fue del 3,3% (15) pacientes. La principal causa de muerte fue infecciosa (73,3%). La hospitalización hasta la primera infección (ORa: 1,61), el número de infecciones en 1 año (ORa: 40,16) y la infección por citomegalovirus (ORa: 13,84) fueron factores de riesgo de infección por microorganismos multirresistentes (MR). Conclusión: La incidencia de infección bacteriana por MR fue alta entre los receptores de trasplante renal DFCE y la principal causa de muerte fue la infección. La supervivencia fue alta entre los pacientes con infección.

RESUMO Objetivo: Analisar fatores de risco para infecção em receptores de transplante renal de doador falecido com critério expandido (DFCE) nos primeiros dois anos de seguimento. Método: Trata-se de estudo de coorte prospectivo, com 466 pacientes do DFCE submetidos a transplante renal, em 2015 e 2016, no Brasil. Um total de 551 eventos foram registrados. A maior incidência de eventos infecciosos ocorreu no primeiro mês após o transplante renal. A infecção por citomegalovírus foi o episódio infeccioso mais comum. Resultados: A taxa de incidência de infecções foi de 57,1%. Entre as infecções bacterianas, apenas 4% foram devidas a microrganismos multirresistentes. A taxa de mortalidade foi de 3,3% (15) pacientes. A principal causa de morte foi infecciosa (73,3%). Hospitalização até a primeira infecção (ORa: 1,61), número de infecções em 1 ano (ORa: 40,16) e infecção por citomegalovírus (ORa: 13,84) foram fatores de risco para infecção por microrganismos multirresistentes (MR). Conclusão: A incidência de infecção por bactérias MR foi alta entre receptores de transplante renal de DFCE, e a principal causa de morte foi infecção. A sobrevivência foi alta entre os pacientes com infecção.

Functional capacity and quality of life of elderly people admitted to emergency service. / Capacidade funcional e qualidade de vida de pessoas idosas internadas no serviço de emergência.

OBJECTIVE: To correlate the functional capacity and quality of life of elderly people admitted to emergency service. METHOD: This is a cross-sectional and analytical study carried out with elderly patients admitted to a university hospital's emergency service in the city of São Paulo, between December 2015 and January 2017. Data were collected through interviews using a structured questionnaire, the Medical Outcome Study 36, the Katz of Independence in Activities of Daily Living, and the Functional Independence Measure. RESULTS: Two hundred fifty elderly people with a mean age of 71.9 years, male (56.8%), white in color (67.2%), married (54.0%), with low education (32.0%), low income (58.0%), with comorbidities (81.2%) and home providers (53.6%) have participated. The most compromised Quality of Life dimensions were physical aspect (11.4%), emotional aspect (21.6%) and functional capacity (25.2%). Concerning functional capacity, independence was characterized for Basic Activities of Daily Living and moderate dependence for Instrumental Activities of Daily Living. The higher the scores of the Functional Independence Measure, the higher the quality of life scores. CONCLUSION: The more independent the elderly the better their quality of life.

Quality of life and spirituality of patients with chronic kidney disease: pre- and post-transplant analysis.

OBJECTIVE: to compare the quality of life (QoL) of patients under dialysis and after kidney transplant; correlate the QoL of transplant patients to sociodemographic, morbid and spirituality/religiosity variables. METHOD: prospective study with a quantitative approach, with a sample of 27 patients who underwent peritoneal dialysis or dialysis undergoing kidney transplant. QoL and spirituality were assessed by the KDQOL-SF and WHOQOL-SRPB tools, being correlated with sociodemographic and economic variables. RESULTS: the dimensions of total mental component, kidney disease effects and kidney disease burden showed significant improvement in the post-transplant period, with p <0.0004. There was a significant correlation between four dimensions of spirituality and seven dimensions of QoL; p ranged from 0.04 to 0.006. CONCLUSION: there was a significant improvement in QoL in the post-transplant period. The dimensions of spirituality: wholeness and integration, spiritual connection, wonder and inner peace were positively correlated with seven dimensions of QoL.

Quality of life and body image of patients with urinary disorders.

OBJECTIVE: to assess the quality of life and body image of men with difficulty urinating and indwelling urinary catheter users, integrating the socio-demographic, economic and morbidity variables. METHOD: a cross-sectional analytical study with 64 male patients with urinary problems. Three questionnaires were used for data collection: one containing sociodemographic, economic and morbid data, the Medical Outcome Study 36-item short-form health survey to analyze quality of life, and the Body Dysmorphic Examination, which assesses body image. T-test, Mann-Whitney, Pearson, Spearman, Linear Regression and Stepwise were used. RESULTS: quality of life and body image were compromised in both groups, affecting emotional aspects, with a high degree of body dissatisfaction and altered physical and social adversity. CONCLUSION: changes in patients' quality of life and body image were observed, confirming the need for improvement in care.

Satisfação com a vida, qualidade de vida e capacidade funcional de octogenários hospitalizados / Satisfacción con la vida, calidad de vida y capacidad funcional de pacientes octogenarios hospitalizados / Life satisfaction, quality of life and functional capacity of hospitalized octogenaries

RESUMO Objetivos: correlacionar satisfação com a vida com qualidade de vida e capacidade funcional em idosos hospitalizados. Método: estudo transversal com 128 octogenários. Aplicados instrumentos de qualidade de vida da Organização Mundial da Saúde, Escalas de Satisfação com a Vida e Katz. Resultados: quanto mais altos os escores aspectos saúde física, capacidade física e envolvimento social da Escala de Satisfação com a Vida, mais altos os escores nos domínios físico, psicológico, relações sociais, meio ambiente, percepção da qualidade de vida e satisfação com a saúde do instrumento de qualidade de vida. Quanto maiores os domínios funcionamento do sensório, autonomia, atividades passadas, presentes e futuras, participação social, qualidade de vida geral e qualidade de vida, maiores os escores aspectos saúde física, saúde mental, capacidade física e envolvimento social da Escala de Satisfação com a Vida. Pacientes independentes apresentaram maiores escores aspectos saúde física e saúde mental da Escala de Satisfação com a Vida quando comparados aos com grau máximo de dependência. Conclusão: os resultados permitem orientar estratégias de cuidado aos profissionais de saúde que trabalham com idosos.

RESUMEN Objetivo: correlacionar la satisfacción con la vida con la calidad de vida y la capacidad funcional en adultos mayores hospitalizados. Método: estudio transversal con 128 pacientes octogenarios. Se utilizaron instrumentos de calidad de vida de la Organización Mundial de la Salud, Escalas de Satisfacción con la Vida y Katz. Resultados: cuanto mayor era la puntuación en los aspectos salud física, capacidad física y compromiso social en la escala de satisfacción con la vida, más alta era la puntuación en los campos físico, psicológico, relaciones sociales, medio ambiente, percepción de la calidad de vida y satisfacción con la salud del instrumento de calidad de vida. Cuanto mayores eran los dominios de funcionamiento sensorial, autonomía, actividades pasadas, presentes y futuras, participación social, calidad de vida en general y calidad de vida, mayor era la puntuación en salud física, salud mental, capacidad física ycompromiso social de la Escala de Satisfacción con la Vida. Los pacientes independientes obtuvieron puntuaciones más altas en los aspectos salud física y mental de la Escala de Satisfacción con la Vida en comparación con aquéllos connivel máximo de dependencia. Conclusión: los resultados permiten orientar estrategias de atención a los profesionales de la salud que trabajan con adultos mayores.

ABSTRACT Objectives: to correlate life satisfaction with quality of life and functional capacity in hospitalized elderly. Method: cross-sectional study with 128 octogenarians. World Health Organization quality of life instruments applied, Life Satisfaction Scales and Katz. Results: the higher the scores for physical health, physical capacity and social involvement in the Life Satisfaction Scale, the higher the scores in the physical, psychological, social relations, environment, perception of quality of life and health satisfaction of the quality of life instrument. The larger the domains of sensory functioning, autonomy, past, present and future activities, social participation, general quality of life and quality of life, the higher the scores on physical health, mental health, physical capacity and social involvement of the Satisfaction Scale with Life. Independent patients had higher scores on physical and mental health aspects of the Life Satisfaction Scale when compared to those with a maximum degree of dependence. Conclusion: the results allow guiding care strategies to health professionals who work with the elderly.

Quality of life and cognitive and functional performance of octogenarians and nonagenarians undergoing hemodialysis.

OBJECTIVE: To evaluate the quality of life, cognitive and functional capacity of older adult patients undergoing hemodialysis who are 80 years of age or older and compare them to older adults without chronic kidney disease (CKD) treated at a geriatrics outpatient clinic. METHOD: First, 103 older adult patients undergoing hemodialysis and 103 older adults without CKD matched by gender and age were evaluated. Cognitive aspects as evaluated by the mini mental state examination, the Boston Naming Test and verbal fluency were analyzed; comorbidities according to the Charlson's comorbidity index; social support through the Medical Outcomes Study scale; functional ability through the chair sit-to-stand and gait speed tests, as well as the basic activities of daily living (BADL) and instrumental activities of daily living (IADL) and quality of life according to the Kidney Disease Quality of Life Short Form (KDQOL SF-36) questionnaires. RESULTS: The hemodialysis group had a higher rate of comorbidities (7.8 ± 2.4 vs. 5.8 ± 2.3, p < 0.001). In the multiple logistic regression analysis, the group undergoing hemodialysis presented a ninefold greater chance of dependence for IADL than controls, a 4.3 and 3.2 times greater chances for inadequacy on the gait speed and chair sit-to-stand tests, respectively, as well as a 4.4-fold higher risk of cognitive decline on the verbal fluency test. CONCLUSION: Long-lived patients undergoing hemodialysis presented worse quality of life and functional and cognitive performance compared to long-term patients attended at the outpatient clinic, indicating that preventive and protective measures should be considered and implemented.